DNA repair in cancer therapy

Descripción

This volume is concerned with the hallmark "relapse" or "drug resistance" phenomena that face the practicing oncologist on a daily basis and it serves as a translational reference for clinical applications. It covers the increasing evidence that impaired expression/activity of at least some of the DNA repair proteins account for tumor cell resistance to particular therapeutic agents. This book summarizes timely in-depth reviews covering the latest developments that have potential for translational and clinical applications and represents the first volume dedicated to the translational aspect of DNA repair in the clinic.